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Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid
Cleavage and polyadenylation specificity factor 6 (CPSF6) is a human protein that binds HIV-1 capsid and mediates nuclear transport and integration targeting of HIV-1 preintegration complexes. Truncation of the protein at its C-terminal nuclear-targeting arginine/serine-rich (RS) domain produces a p...
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| Publicado no: | J Virol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002704/ https://ncbi.nlm.nih.gov/pubmed/29643241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00368-18 |
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