Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid

Cleavage and polyadenylation specificity factor 6 (CPSF6) is a human protein that binds HIV-1 capsid and mediates nuclear transport and integration targeting of HIV-1 preintegration complexes. Truncation of the protein at its C-terminal nuclear-targeting arginine/serine-rich (RS) domain produces a p...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Ning, Jiying, Zhong, Zhou, Fischer, Douglas K., Harris, Gemma, Watkins, Simon C., Ambrose, Zandrea, Zhang, Peijun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Virus-Cell Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002704/
https://ncbi.nlm.nih.gov/pubmed/29643241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00368-18
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