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A Carboxy-Terminally Truncated Human CPSF6 Lacking Residues Encoded by Exon 6 Inhibits HIV-1 cDNA Synthesis and Promotes Capsid Disassembly

Since HIV-1 replication is modulated at multiple stages by host cell factors, identification and characterization of those host cell factors are expected to contribute to the development of novel anti-HIV therapeutics. Previous studies showed that a C-terminally truncated cytosolic form of cleavage...

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Hlavní autoři: Hori, Takanori, Takeuchi, Hiroaki, Saito, Hideki, Sakuma, Ryuta, Inagaki, Yoshio, Yamaoka, Shoji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700264/
https://ncbi.nlm.nih.gov/pubmed/23658440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00124-13
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