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The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability

JC polyomavirus (JCV), a DNA virus that leads to persistent infection in humans, is the causative agent of progressive multifocal leukoencephalopathy, a lethal brain disease that affects immunocompromised individuals. Almost nothing is currently known about how JCV infection is controlled by the inn...

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Bibliografiska uppgifter
I publikationen:mBio
Huvudupphovsmän: Chiang, Cindy, Dvorkin, Steve, Chiang, Jessica J., Potter, Rachel B., Gack, Michaela U.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092259/
https://ncbi.nlm.nih.gov/pubmed/33849980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00620-21
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