Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway

Antiviral response pathways induce interferon by higher-order assembly of signaling complexes called signalosomes. Assembly of the RIG-I signalosome is regulated by K63-linked polyubiquitin chains, which are synthesized by the E3 ubiquitin ligase, TRIM25. We have previously shown that the TRIM25 coi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Sanchez, Jacint G., Chiang, Jessica J., Sparrer, Konstantin M.J., Alam, Steven L., Chi, Michael, Roganowicz, Marcin D., Sankaran, Banumathi, Gack, Michaela U., Pornillos, Owen
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076470/
https://ncbi.nlm.nih.gov/pubmed/27425606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.070
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki