TRIM25 binds RNA to modulate cellular anti-viral defense

TRIM25 is a multi-domain, RING-type E3 ubiquitin ligase of the tripartite motif family that has important roles in multiple RNA-dependent processes. In particular, TRIM25 functions as an effector of RIG-I and ZAP, which are innate immune sensors that recognize viral RNA and induce ubiquitin-dependen...

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Foilsithe in:J Mol Biol
Main Authors: Sanchez, Jacint G., Sparrer, Konstantin M.J., Chiang, Cindy, Reis, Rebecca A., Chiang, Jessica J., Zurenski, Matthew A., Wan, Yueping, Gack, Michaela U., Pornillos, Owen
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289755/
https://ncbi.nlm.nih.gov/pubmed/30342007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.10.003
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