A carregar...
Linear ubiquitin assembly complex negatively regulates RIG-I and TRIM25 mediated type-I interferon induction
Upon detection of viral RNA, retinoic acid inducible gene I (RIG-I) undergoes TRIM25-mediated Lys-63 linked ubiquitination, leading to type-I interferon (IFN) production. In this study, we demonstrate that the linear ubiquitin assembly complex (LUBAC), comprised of two RING-IBR-RING (RBR)-containing...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070481/ https://ncbi.nlm.nih.gov/pubmed/21292167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.029 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|