Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy

Multiple system atrophy (MSA) is an insidious middle age-onset neurodegenerative disease that clinically presents with variable degrees of parkinsonism and cerebellar ataxia. The pathological hallmark of MSA is the progressive accumulation of glial cytoplasmic inclusions (GCIs) in oligodendrocytes t...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Hass, Ethan W., Sorrentino, Zachary A., Lloyd, Grace M., McFarland, Nikolaus R., Prokop, Stefan, Giasson, Benoit I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091528/
https://ncbi.nlm.nih.gov/pubmed/33941284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01173-y
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