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Endogenous Oligodendroglial Alpha-Synuclein and TPPP/p25α Orchestrate Alpha-Synuclein Pathology in Experimental Multiple System Atrophy Models

Multiple system atrophy (MSA) is characterized by the presence of distinctive glial cytoplasmic inclusions (GCIs) within oligodendrocytes that contain the neuronal protein alpha-synuclein (aSyn) and the oligodendroglia-specific phosphoprotein TPPP/p25α. However, the role of oligodendroglial aSyn and...

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Foilsithe in:Acta Neuropathol
Main Authors: Mavroeidi, Panagiota, Arvanitaki, Fedra, Karakitsou, Anastasia-Kiriaki, Vetsi, Maria, Kloukina, Ismini, Zweckstetter, Markus, Giller, Karin, Becker, Stefan, Sorrentino, Zachary A., Giasson, Benoit I., Henning Jensen, Poul, Stefanis, Leonidas, Xilouri, Maria
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289399/
https://ncbi.nlm.nih.gov/pubmed/31011860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02014-y
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