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Loss of sarcospan exacerbates pathology in mdx mice, but does not affect utrophin amelioration of disease
The dystrophin–glycoprotein complex (DGC) is a membrane adhesion complex that provides structural stability at the sarcolemma by linking the myocyte’s internal cytoskeleton and external extracellular matrix. In Duchenne muscular dystrophy (DMD), the absence of dystrophin leads to the loss of the DGC...
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| Publicado no: | Hum Mol Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091037/ https://ncbi.nlm.nih.gov/pubmed/33432327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa264 |
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