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GH Is a Component of SASP in Aging Tissue
Deficient GH signaling results in lifespan extension in murine and human models, while patients with uncontrolled acromegaly and transgenic mice overexpressing GH have a shorter lifespan. Colon polyp development increases with age, and also with GH excess in acromegaly. Aging is characterized by sen...
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| Publicado no: | J Endocr Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8090645/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1099 |
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