OR16-06 Age-Associated Local GH Promotes Colon Neoplasia

Colon polyp and cancer frequency increase with age, yet little is known about age-related mechanisms underlying development of these neoplasms. Defective DNA damage response and accumulation of unrepaired DNA damage can trigger genomic instability and cellular transformation. Patients with acromegal...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Chesnokova, Vera M, Zonis, Svetlana, Apostolou, Nasia, Hannah, Estrada Q, Knott, Simon, Wawrowsky, Kolja, Ben-Shlomo, Anat, Barrett, Robert, Gorbunova, Vera, Karalis, Katia, Melmed, Shlomo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Neuroendocrinology and Pituitary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208399/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1474
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