Differential Activity and Utilization of Glucocorticoid Receptor Binding Sites Yields Transcriptional Heterogeneity

Synthetic glucocorticoids such as Dexamethasone (Dex) are widely prescribed drugs used to treat a variety of human diseases including auto-immune disorders, asthma, cancer, and COVID-19. The transcriptional response to glucocorticoids is elicited by the Glucocorticoid Receptor (GR), which enters the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Endocr Soc
Egile Nagusiak: Hoffman, Jackson Andrew, Trotter, Kevin W, Day, Christopher R, Ward, James M, Rodriguez, Joseph, Archer, Trevor K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2021
Gaiak:
Genetics and Development (including Gene Regulation)
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090539/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1021
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak