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BRG1 governs glucocorticoid receptor interactions with chromatin and pioneer factors across the genome

The Glucocorticoid Receptor (GR) alters transcriptional activity in response to hormones by interacting with chromatin at GR binding sites (GBSs) throughout the genome. Our work in human breast cancer cells identifies three classes of GBSs with distinct epigenetic characteristics and reveals that BR...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hoffman, Jackson A, Trotter, Kevin W, Ward, James M, Archer, Trevor K
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967868/
https://ncbi.nlm.nih.gov/pubmed/29792595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35073
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