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Glucocorticoid Receptor Transcriptional Activation via the BRG1-Dependent Recruitment of TOP2β and Ku70/86

BRG1, the central ATPase of the human SWI/SNF complex, is critical for biological functions, including nuclear receptor (NR)-regulated transcription. Analysis of BRG1 mutants demonstrated that functional motifs outside the ATPase domain are important for transcriptional activity. In the course of ex...

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Pubblicato in:Mol Cell Biol
Autori principali: Trotter, Kevin W., King, Heather A., Archer, Trevor K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508321/
https://ncbi.nlm.nih.gov/pubmed/26055322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00230-15
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