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Single-cell RNA sequencing reveals a heterogeneous response to Glucocorticoids in breast cancer cells

Steroid hormone receptors such as the Glucocorticoid Receptor (GR) mediate transcriptional responses to hormones and are frequently targeted in the treatment of human diseases. Experiments using bulk populations of cells have provided a detailed picture of the global transcriptional hormone response...

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Udgivet i:Commun Biol
Main Authors: Hoffman, Jackson A., Papas, Brian N., Trotter, Kevin W., Archer, Trevor K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070043/
https://ncbi.nlm.nih.gov/pubmed/32170217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0837-0
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