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High-resolution, ultra-sensitive and quantitative DNA double-strand break labeling in eukaryotic cells using i-BLESS
DNA double-strand breaks (DSBs) are implicated in various physiological processes, such as class-switch recombination or crossing-over during meiosis, but also present a threat to genome stability. Extensive evidence shows that DSBs are a primary source of chromosome translocations or deletions, mak...
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| Veröffentlicht in: | Nat Protoc |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8088906/ https://ncbi.nlm.nih.gov/pubmed/33349705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-00448-3 |
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