Genome wide mapping of long range contacts unveils DNA Double Strand Breaks clustering at damaged active genes

The ability of DNA Double Strand Breaks (DSBs) to cluster in mammalian cells has been subjected to intense debate over the past few years. Here we used a high throughput chromosome conformation capture assay (Capture Hi-C) to investigate clustering of DSBs induced at defined loci in the human genome...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Aymard, François, Aguirrebengoa, Marion, Guillou, Emmanuelle, Javierre, Biola M, Bugler, Beatrix, Arnould, Coline, Rocher, Vincent, Iacovoni, Jason S, Biernacka, Anna, Skrzypczak, Magdalena, Ginalski, Krzysztof, Rowicka, Maga, Fraser, Peter, Legube, Gaëlle
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385132/
https://ncbi.nlm.nih.gov/pubmed/28263325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3387
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados