Genome wide mapping of long range contacts unveils DNA Double Strand Breaks clustering at damaged active genes

The ability of DNA Double Strand Breaks (DSBs) to cluster in mammalian cells has been subjected to intense debate over the past few years. Here we used a high throughput chromosome conformation capture assay (Capture Hi-C) to investigate clustering of DSBs induced at defined loci in the human genome...

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書誌詳細
出版年:Nat Struct Mol Biol
主要な著者: Aymard, François, Aguirrebengoa, Marion, Guillou, Emmanuelle, Javierre, Biola M, Bugler, Beatrix, Arnould, Coline, Rocher, Vincent, Iacovoni, Jason S, Biernacka, Anna, Skrzypczak, Magdalena, Ginalski, Krzysztof, Rowicka, Maga, Fraser, Peter, Legube, Gaëlle
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385132/
https://ncbi.nlm.nih.gov/pubmed/28263325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3387
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