Cohesin Protects Genes against γH2AX Induced by DNA Double-Strand Breaks

Chromatin undergoes major remodeling around DNA double-strand breaks (DSB) to promote repair and DNA damage response (DDR) activation. We recently reported a high-resolution map of γH2AX around multiple breaks on the human genome, using a new cell-based DSB inducible system. In an attempt to further...

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Hauptverfasser: Caron, Pierre, Aymard, Francois, Iacovoni, Jason S., Briois, Sébastien, Canitrot, Yvan, Bugler, Beatrix, Massip, Laurent, Losada, Ana, Legube, Gaëlle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261922/
https://ncbi.nlm.nih.gov/pubmed/22275873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002460
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