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Transcriptionally active chromatin recruits homologous recombination at DNA double strand breaks
While both Homologous recombination (HR) and Non Homologous End Joining (NHEJ) can repair DNA double Strand Breaks (DSB), the mechanisms by which one or other of these pathways is chosen remain unclear. Here we show that transcriptionally active chromatin is preferentially repaired by HR. Using chro...
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| 出版年: | Nat Struct Mol Biol |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4300393/ https://ncbi.nlm.nih.gov/pubmed/24658350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2796 |
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