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qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing
DNA double-strand breaks (DSBs) are among the most lethal types of DNA damage and frequently cause genome instability. Sequencing-based methods for mapping DSBs have been developed but they allow measurement only of relative frequencies of DSBs between loci, which limits our understanding of the phy...
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| Опубликовано в: : | Nat Commun |
|---|---|
| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534554/ https://ncbi.nlm.nih.gov/pubmed/31127121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10332-8 |
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