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Stochasticity of replication forks’ speeds plays a key role in the dynamics of DNA replication

Eukaryotic DNA replication is elaborately orchestrated to duplicate the genome timely and faithfully. Replication initiates at multiple origins from which replication forks emanate and travel bi-directionally. The complex spatio-temporal regulation of DNA replication remains incompletely understood....

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Yousefi, Razie, Rowicka, Maga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975548/
https://ncbi.nlm.nih.gov/pubmed/31869320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007519
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