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Stochasticity of replication forks’ speeds plays a key role in the dynamics of DNA replication

Eukaryotic DNA replication is elaborately orchestrated to duplicate the genome timely and faithfully. Replication initiates at multiple origins from which replication forks emanate and travel bi-directionally. The complex spatio-temporal regulation of DNA replication remains incompletely understood....

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Pubblicato in:PLoS Comput Biol
Autori principali: Yousefi, Razie, Rowicka, Maga
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975548/
https://ncbi.nlm.nih.gov/pubmed/31869320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007519
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