qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing

DNA double-strand breaks (DSBs) are among the most lethal types of DNA damage and frequently cause genome instability. Sequencing-based methods for mapping DSBs have been developed but they allow measurement only of relative frequencies of DSBs between loci, which limits our understanding of the phy...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Zhu, Yingjie, Biernacka, Anna, Pardo, Benjamin, Dojer, Norbert, Forey, Romain, Skrzypczak, Magdalena, Fongang, Bernard, Nde, Jules, Yousefi, Razie, Pasero, Philippe, Ginalski, Krzysztof, Rowicka, Maga
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534554/
https://ncbi.nlm.nih.gov/pubmed/31127121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10332-8
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