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Serine protease dynamics revealed by NMR analysis of the thrombin-thrombomodulin complex
Serine proteases catalyze a multi-step covalent catalytic mechanism of peptide bond cleavage. It has long been assumed that serine proteases including thrombin carry-out catalysis without significant conformational rearrangement of their stable two-β-barrel structure. We present nuclear magnetic res...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8087772/ https://ncbi.nlm.nih.gov/pubmed/33931701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88432-z |
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