Загрузка...
SRP54 Negatively Regulates IFN-Beta Production and Antiviral Response by Targeting RIG-I and MDA5
During virus infection, RIG-I-like receptors (RLRs) recognize viral RNAs and recruit the adaptor protein VISA to activate downstream signaling, leading to activation of transcription factors NF-κB and IRF3, which collaborate to induce type I interferons (IFNs). IFNs further induce expression of hund...
Сохранить в:
| Опубликовано в: : | Virol Sin |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Singapore
2020
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8087748/ https://ncbi.nlm.nih.gov/pubmed/32767210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-020-00267-6 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|