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Phosphorylation-Mediated Negative Regulation of RIG-I Antiviral Activity
Recognition of invading viruses by the host is elicited by cellular sensors which trigger signaling cascades that lead to type I interferon (IFN) gene expression. Retinoic acid-inducible gene I (RIG-I) has emerged as a key receptor for the detection of viral RNA in the cytosol, inducing IFN-mediated...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838087/ https://ncbi.nlm.nih.gov/pubmed/20071582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02241-09 |
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