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LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses
RNA virus infection is recognized by retinoic acid-inducible gene (RIG)-I–like receptors (RLRs), RIG-I, and melanoma differentiation–associated gene 5 (MDA5) in the cytoplasm. RLRs are comprised of N-terminal caspase-recruitment domains (CARDs) and a DExD/H-box helicase domain. The third member of t...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824407/ https://ncbi.nlm.nih.gov/pubmed/20080593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912986107 |
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