LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses

RNA virus infection is recognized by retinoic acid-inducible gene (RIG)-I–like receptors (RLRs), RIG-I, and melanoma differentiation–associated gene 5 (MDA5) in the cytoplasm. RLRs are comprised of N-terminal caspase-recruitment domains (CARDs) and a DExD/H-box helicase domain. The third member of t...

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Detalhes bibliográficos
Main Authors: Satoh, Takashi, Kato, Hiroki, Kumagai, Yutaro, Yoneyama, Mitsutoshi, Sato, Shintaro, Matsushita, Kazufumi, Tsujimura, Tohru, Fujita, Takashi, Akira, Shizuo, Takeuchi, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824407/
https://ncbi.nlm.nih.gov/pubmed/20080593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912986107
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