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Peptide Derivatives of Retinylamine Prevent Retinal Degeneration with Minimal Side Effects on Vision in Mice

Safe and effective molecular therapeutics for prophylactic treatment of retinal degenerative diseases are greatly needed. Disruptions in the clearance of all-trans-retinal (atRAL) by the visual (retinoid) cycle of the retina can lead to the accumulation of atRAL and its condensation products known t...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Yu, Guanping, Gao, Song-Qi, Dong, Zhiqian, Sheng, Li, Sun, Da, Zhang, Ning, Zhang, Jianye, Margeivicus, Seunghee, Fu, Pingfu, Golczak, Marcin, Maeda, Akiko, Palczewski, Krzysztof, Lu, Zheng-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087159/
https://ncbi.nlm.nih.gov/pubmed/33677964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.1c00043
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