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Peptide Derivatives of Retinylamine Prevent Retinal Degeneration with Minimal Side Effects on Vision in Mice

Safe and effective molecular therapeutics for prophylactic treatment of retinal degenerative diseases are greatly needed. Disruptions in the clearance of all-trans-retinal (atRAL) by the visual (retinoid) cycle of the retina can lead to the accumulation of atRAL and its condensation products known t...

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Dades bibliogràfiques
Publicat a:Bioconjug Chem
Autors principals: Yu, Guanping, Gao, Song-Qi, Dong, Zhiqian, Sheng, Li, Sun, Da, Zhang, Ning, Zhang, Jianye, Margeivicus, Seunghee, Fu, Pingfu, Golczak, Marcin, Maeda, Akiko, Palczewski, Krzysztof, Lu, Zheng-Rong
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087159/
https://ncbi.nlm.nih.gov/pubmed/33677964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.1c00043
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