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Peptide Derivatives of Retinylamine Prevent Retinal Degeneration with Minimal Side Effects on Vision in Mice

Safe and effective molecular therapeutics for prophylactic treatment of retinal degenerative diseases are greatly needed. Disruptions in the clearance of all-trans-retinal (atRAL) by the visual (retinoid) cycle of the retina can lead to the accumulation of atRAL and its condensation products known t...

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Bibliografiska uppgifter
I publikationen:Bioconjug Chem
Huvudupphovsmän: Yu, Guanping, Gao, Song-Qi, Dong, Zhiqian, Sheng, Li, Sun, Da, Zhang, Ning, Zhang, Jianye, Margeivicus, Seunghee, Fu, Pingfu, Golczak, Marcin, Maeda, Akiko, Palczewski, Krzysztof, Lu, Zheng-Rong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087159/
https://ncbi.nlm.nih.gov/pubmed/33677964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.1c00043
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