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Unifying Model of Domain Architecture for Conventional and Novel Protein Kinase C Isozymes

Protein kinase C family members are multi-domain proteins whose function is exquisitely tuned by inter-domain interactions that control the spatiotemporal dynamics of their signaling. Despite extensive mechanistic studies on this family of enzymes, no structure of a full-length enzyme that includes...

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Bibliographische Detailangaben
Veröffentlicht in:IUBMB Life
Hauptverfasser: Jones, Alexander, Taylor, Susan S., Newton, Alexandra C., Kornev, Alexandr P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086893/
https://ncbi.nlm.nih.gov/pubmed/33166426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.2401
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