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Disordered Protein Kinase Regions in Regulation of Kinase Domain Cores
Since publication of the crystal structure of protein kinase (PK)A three decades ago, a structural portrait of the conserved kinase core has been drawn. The next challenge is to elucidate structures of full-length kinases and to address the intrinsically disordered regions (IDRs) that typically flan...
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| Udgivet i: | Trends Biochem Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6592696/ https://ncbi.nlm.nih.gov/pubmed/30611608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.12.002 |
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