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Genetic Manipulation of Sirtuin 3 Causes Alterations of Key Metabolic Regulators in Melanoma

The mitochondrial sirtuin SIRT3 plays key roles in cellular metabolism and energy production, which makes it an obvious target for the management of cancer, including melanoma. Previously, we have demonstrated that SIRT3 was constitutively upregulated in human melanoma and its inhibition resulted in...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Singh, Chandra K., George, Jasmine, Chhabra, Gagan, Nihal, Minakshi, Chang, Hao, Ahmad, Nihal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085490/
https://ncbi.nlm.nih.gov/pubmed/33937086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.676077
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