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Genetic Manipulation of Sirtuin 3 Causes Alterations of Key Metabolic Regulators in Melanoma

The mitochondrial sirtuin SIRT3 plays key roles in cellular metabolism and energy production, which makes it an obvious target for the management of cancer, including melanoma. Previously, we have demonstrated that SIRT3 was constitutively upregulated in human melanoma and its inhibition resulted in...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Singh, Chandra K., George, Jasmine, Chhabra, Gagan, Nihal, Minakshi, Chang, Hao, Ahmad, Nihal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085490/
https://ncbi.nlm.nih.gov/pubmed/33937086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.676077
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