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4′-Bromo-Resveratrol, a Dual Sirtuin-1 and Sirtuin-3 Inhibitor, Inhibits Melanoma Cell Growth Through Mitochondrial Metabolic Reprogramming
Sirtuin-1 and -3 (SIRT1 and SIRT3) are important NAD(+)-dependent deacetylases known to regulate a variety of cellular functions. Studies have shown that SIRT1 and SIRT3 were overexpressed in human melanoma cells and tissues and their inhibition resulted in a significant antiproliferative response i...
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| Publicado no: | Mol Carcinog |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6721992/ https://ncbi.nlm.nih.gov/pubmed/31292999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23080 |
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