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Genetic Manipulation of Sirtuin 3 Causes Alterations of Key Metabolic Regulators in Melanoma

The mitochondrial sirtuin SIRT3 plays key roles in cellular metabolism and energy production, which makes it an obvious target for the management of cancer, including melanoma. Previously, we have demonstrated that SIRT3 was constitutively upregulated in human melanoma and its inhibition resulted in...

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Bibliografische gegevens
Gepubliceerd in:Front Oncol
Hoofdauteurs: Singh, Chandra K., George, Jasmine, Chhabra, Gagan, Nihal, Minakshi, Chang, Hao, Ahmad, Nihal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085490/
https://ncbi.nlm.nih.gov/pubmed/33937086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.676077
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