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Genetic Manipulation of Sirtuin 3 Causes Alterations of Key Metabolic Regulators in Melanoma

The mitochondrial sirtuin SIRT3 plays key roles in cellular metabolism and energy production, which makes it an obvious target for the management of cancer, including melanoma. Previously, we have demonstrated that SIRT3 was constitutively upregulated in human melanoma and its inhibition resulted in...

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Podrobná bibliografie
Vydáno v:Front Oncol
Hlavní autoři: Singh, Chandra K., George, Jasmine, Chhabra, Gagan, Nihal, Minakshi, Chang, Hao, Ahmad, Nihal
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085490/
https://ncbi.nlm.nih.gov/pubmed/33937086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.676077
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