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DNA Double-Strand Breaks: A Double-Edged Sword for Trypanosomatids

For nearly all eukaryotic cells, stochastic DNA double-strand breaks (DSBs) are one of the most deleterious types of DNA lesions. DSB processing and repair can cause sequence deletions, loss of heterozygosity, and chromosome rearrangements resulting in cell death or carcinogenesis. However, trypanos...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Dev Biol
Hoofdauteur: da Silva, Marcelo Santos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085331/
https://ncbi.nlm.nih.gov/pubmed/33937271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.669041
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