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DNA Double-Strand Breaks: A Double-Edged Sword for Trypanosomatids

For nearly all eukaryotic cells, stochastic DNA double-strand breaks (DSBs) are one of the most deleterious types of DNA lesions. DSB processing and repair can cause sequence deletions, loss of heterozygosity, and chromosome rearrangements resulting in cell death or carcinogenesis. However, trypanos...

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Bibliografiska uppgifter
I publikationen:Front Cell Dev Biol
Huvudupphovsman: da Silva, Marcelo Santos
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085331/
https://ncbi.nlm.nih.gov/pubmed/33937271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.669041
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