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Structure-forming repeats and their impact on genome stability
Repetitive sequences throughout the genome are a major source of endogenous DNA damage, due to the propensity of many of them to form alternative non-B DNA structures that can interfere with replication, transcription, and DNA repair. These repetitive sequences are prone to breakage (fragility) and...
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| Publicado en: | Curr Opin Genet Dev |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8084909/ https://ncbi.nlm.nih.gov/pubmed/33279816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2020.10.006 |
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