Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability

Secondary structure-forming DNA sequences such as CAG repeats interfere with replication and repair, provoking fork stalling, chromosome fragility, and recombination. In budding yeast, we found that expanded CAG repeats are more likely than unexpanded repeats to localize to the nuclear periphery. Th...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Su, Xiaofeng A., Dion, Vincent, Gasser, Susan M., Freudenreich, Catherine H.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441049/
https://ncbi.nlm.nih.gov/pubmed/25940904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.256404.114
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