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Triplet repeats form secondary structures that escape DNA repair in yeast

Several human neurodegenerative diseases result from expansion of CTG/CAG or CGG/CCG triplet repeats. The finding that single-stranded CNG repeats form hairpin-like structures in vitro has led to the hypothesis that DNA secondary structure formation is an important component of the expansion mechani...

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Bibliografski detalji
Glavni autori: Moore, Hutton, Greenwell, Patricia W., Liu, Chin-Pin, Arnheim, Norman, Petes, Thomas D.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC15496/
https://ncbi.nlm.nih.gov/pubmed/9990053
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