Triplet repeats form secondary structures that escape DNA repair in yeast

Several human neurodegenerative diseases result from expansion of CTG/CAG or CGG/CCG triplet repeats. The finding that single-stranded CNG repeats form hairpin-like structures in vitro has led to the hypothesis that DNA secondary structure formation is an important component of the expansion mechani...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Moore, Hutton, Greenwell, Patricia W., Liu, Chin-Pin, Arnheim, Norman, Petes, Thomas D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15496/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1504
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