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Structure-forming repeats and their impact on genome stability

Repetitive sequences throughout the genome are a major source of endogenous DNA damage, due to the propensity of many of them to form alternative non-B DNA structures that can interfere with replication, transcription, and DNA repair. These repetitive sequences are prone to breakage (fragility) and...

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Podrobná bibliografie
Vydáno v:Curr Opin Genet Dev
Hlavní autoři: Brown, Rebecca E., Freudenreich, Catherine H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084909/
https://ncbi.nlm.nih.gov/pubmed/33279816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2020.10.006
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