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Mass Balance Study of the Engineered Cationic Antimicrobial Peptide, WLBU2, Following a Single Intravenous Dose of 14C-WLBU2 in Mice
BACKGROUND: To address multidrug resistance, we developed engineered cationic antimicrobial peptides (eCAPs). Lead eCAP WLBU2 displays potent activity against drug-resistant bacteria and effectively treats lethal bacterial infections in mice, reducing bacterial loads to undetectable levels in divers...
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| Опубликовано в: : | Curr Rev Clin Exp Pharmacol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8083974/ https://ncbi.nlm.nih.gov/pubmed/32778037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1574884715666200810094201 |
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