Enhanced efficacy of the engineered antimicrobial peptide WLBU2 via direct airway delivery in a murine model of P. aeruginosa pneumonia

OBJECTIVES: P. aeruginosa is a common cause of pneumonia in cystic fibrosis patients with the property to generate multidrug resistance against clinically used antibiotics. Antimicrobial peptides (AMPs) are a diverse group of effector molecules of the innate immunity that protect the host against pa...

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Vydáno v:Clin Microbiol Infect
Hlavní autoři: Chen, Chen, Deslouches, Berthony, Montelaro, Ronald C., Di, Y. Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835169/
https://ncbi.nlm.nih.gov/pubmed/28882728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmi.2017.08.029
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