Direct antimicrobial activity of cationic amphipathic peptide WLBU2 against Staphylococcus aureus biofilms is enhanced in physiologic buffered saline

Periprosthetic joint infection of total knee arthroplasties represents a major challenge to the field of orthopaedic surgery. These infections are commonly associated with antibiotic-tolerant Staphylococcus aureus biofilms. Engineered cationic amphipathic peptide WLBU2 has shown the ability to kill...

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Udgivet i:J Orthop Res
Main Authors: Mandell, Jonathan B., Koch, John, Deslouches, Berthony, Urish, Kenneth L.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665995/
https://ncbi.nlm.nih.gov/pubmed/32484998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24765
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