Elimination of Antibiotic Resistant Surgical Implant Biofilms Using an Engineered Cationic Amphipathic Peptide WLBU2

Antibiotics are unable to remove biofilms from surgical implants. This high antibiotic tolerance is related to bacterial persisters, a sub-population of bacteria phenotypically tolerant to antibiotics secondary to a reduced metabolic state. WLBU2 is an engineered cationic amphipathic peptide designe...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Mandell, Jonathan B., Deslouches, Berthony, Montelaro, Ronald C., Shanks, Robert M. Q., Doi, Yohei, Urish, Kenneth L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741726/
https://ncbi.nlm.nih.gov/pubmed/29273750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17780-6
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