Elimination of Antibiotic Resistant Surgical Implant Biofilms Using an Engineered Cationic Amphipathic Peptide WLBU2

Antibiotics are unable to remove biofilms from surgical implants. This high antibiotic tolerance is related to bacterial persisters, a sub-population of bacteria phenotypically tolerant to antibiotics secondary to a reduced metabolic state. WLBU2 is an engineered cationic amphipathic peptide designe...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Mandell, Jonathan B., Deslouches, Berthony, Montelaro, Ronald C., Shanks, Robert M. Q., Doi, Yohei, Urish, Kenneth L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741726/
https://ncbi.nlm.nih.gov/pubmed/29273750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17780-6
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