Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors

PURPOSE: Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a key pathological event in proliferative retinal diseases such as proliferative vitreoretinopathy (PVR). This study aimed to explore a new method to reverse EMT in RPE cells to develop an improved therapy...

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Опубликовано в: :Invest Ophthalmol Vis Sci
Главные авторы: Chen, Yi, Wu, Binxin, He, Jian Feng, Chen, Jingyao, Kang, Zi Wei, Liu, Dandan, Luo, Junjie, Fang, Kexin, Leng, Xiaoxu, Tian, Haibin, Xu, Jingying, Jin, Caixia, Zhang, Jieping, Wang, Juan, Zhang, Jingfa, Ou, Qingjian, Lu, Lixia, Gao, Furong, Xu, Guo-Tong
Формат: Artigo
Язык:Inglês
Опубликовано: The Association for Research in Vision and Ophthalmology 2021
Предметы:
Retinal Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083104/
https://ncbi.nlm.nih.gov/pubmed/33861322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.4.21
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