BMSC-derived extracellular vesicles intervened the pathogenic changes of scleroderma in mice through miRNAs

BACKGROUND: Systemic sclerosis (SSc) is a disease that features severe fibrosis of the skin and lacks effective therapy. Bone marrow mesenchymal stem cell (BMSC)-derived extracellular vesicles (EVs) are potential stem cell-based tools for the treatment of SSc. METHODS: BMSCs were isolated from the b...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Jin, Jiahui, Ou, Qingjian, Wang, Zhe, Tian, Haibin, Xu, Jing-Ying, Gao, Furong, Hu, Shuqin, Chen, Jie, Wang, Juan, Zhang, Jieping, Lu, Lixia, Jin, Caixia, Xu, Guo-Tong, Zhao, Jingjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179710/
https://ncbi.nlm.nih.gov/pubmed/34090522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02400-y
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